Volunteers in Oxford agreed to infect themselves with typhoid, as part of a recently-completed trial of a vaccination that could save the lives of hundreds of thousands of people.
The Oxford Vaccine Group, part of University of Oxford, gave 99 volunteers a drink laced with live Salmonella Typhi bacteria a month after vaccinating them. A third had been vaccinated with Typbar-TCV, a new conjugate typhoid vaccine, a third with established vaccine Typhim Vi and the rest with meningitis vaccine Menveo, which does not protect against typhoid. Neither the volunteers nor the doctors carrying out the injections knew who was getting which vaccine. Continue reading “Oxford vaccine test volunteers infected with typhoid”