What makes tumours tick? Genomics pave the way for tailored treatments

Advances in genetic testing are enabling healthcare professionals to personalise treatments for diseases and conditions including cancer, diabetes and HIV

It’s remarkable how genomics is being used in NHS healthcare, particularly in cancer, where tests now look at the DNA of actual tumours rather than patients. As I have covered previously for ComputerWeekly.com, lung cancer is being targeted through the National Lung Matrix Study. It’s now the case that 15-20% of lung cancer patients can receive targeted treatment based on genomics.

Gary Middleton, professor of medical oncology at the University of Birmingham and chief investigator of the National Lung Matrix Study, put it this way in my new article on this for Guardian Healthcare Professionals Network:

Lung cancer used to be a very simple disease. There were very few treatments and patients did very poorly. It’s really quite complicated now. Keeping on top of the new drugs and the new indications is difficult.

Continue reading “What makes tumours tick? Genomics pave the way for tailored treatments”

Ending 50 years of NHS IT hurt

It was fun to write a piece for Computer Weekly’s 50th anniversary on NHS IT from 1966 to the present, but a depressing pattern emerged. One part of the NHS brings in some state-of-the-art computing; most of the rest of the NHS carries on regardless; progress is not, on the whole, made. The National Programme for IT showed that imposing complicated IT systems from the centre tends to fail, but so has letting the local NHS do its own thing. Continue reading “Ending 50 years of NHS IT hurt”

Coxit map: council reorganisation that breaks up Oxfordshire


Oxfordshire is an odd place. The rural district councils are strongly Conservative; Oxford itself is strongly anyone but the Conservatives. The trend in local government is towards unitary councils which do everything, but how would that work in Oxfordshire?

The simplest model would be a unitary Oxfordshire Council (as in Cornwall and Wiltshire), but Oxford and rural Oxfordshire are politically chalk and cheese. The next option would be to turn the city into a unitary and merge the rural districts into one or more unitaries.

However, a plan from Oxfordshire’s five lower-tier councils endorsed by the county’s MPs is a bit more complicated. Oxford City Council would become a unitary and the two districts in the south of Oxfordshire would merge – South Oxfordshire and Vale of the White Horse already share offices and services. Continue reading “Coxit map: council reorganisation that breaks up Oxfordshire”

The libraries that offer sexual health services and cancer support

Coventry’s Central Library runs health-related events and a mental health drop-in service, reaching people that the NHS can’t

How Coventy City Council works with a local NHS trust to provide advice on sexual health and cancer in its libraries. Continue reading “The libraries that offer sexual health services and cancer support”

Guardian articles on home dialysis and community records

Guardian Healthcare Professionals Network has recently published two pieces by me, one on home dialysis and the other on shared community electronic health records. The first was based on a recent visit to the dialysis service at Nottingham City Hospital, which is piloting the Quanta SC+ dialysis machine.

The trial is taking place in the ward, but the machine is designed for home dialysis – it is a fraction of the size and weight of most. In the photo below, it’s to the left of Ian Hichens, who usually uses home dialysis but was using the ward so he could play the Sugar Plum Fairy in a panto. Continue reading “Guardian articles on home dialysis and community records”